Abstract

A comparison is made between two different approaches to the linear logistic regression analysis of retrospective study data: the prospective model wherein the dependent variable is a dichotomous indicator of case/control status; and the retrospective model wherein the dependent variable is a binary or polychotomous classification of exposure. The two models yield increasingly similar estimates of the relative risk with increasing degrees of covariate adjustment. When the covariate effects are saturated with parameters, the relative risk estimates are identical. The prospective model is generally to be preferred for studies involving multiple quantitative risk factors.

Keywords

CovariateLogistic regressionStatisticsEconometricsRegression analysisVariable (mathematics)MathematicsRegressionRetrospective cohort studyRelative riskMedicineConfidence intervalInternal medicine

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Publication Info

Year
1978
Type
article
Volume
34
Issue
1
Pages
100-100
Citations
93
Access
Closed

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N. E. Breslow, William A. Powers (1978). Are There Two Logistic Regressions for Retrospective Studies?. Biometrics , 34 (1) , 100-100. https://doi.org/10.2307/2529594

Identifiers

DOI
10.2307/2529594