Association of tumour mutational burden with outcomes in patients with advanced solid tumours treated with pembrolizumab: prospective biomarker analysis of the multicohort, open-label, phase 2 KEYNOTE-158 study

2020 The Lancet Oncology 2,300 citations

Keywords

MedicinePembrolizumabInternal medicineResponse Evaluation Criteria in Solid TumorsOncologyCohortMesotheliomaBiomarkerClinical endpointProspective cohort studyCancerProgressive diseaseDiseaseImmunotherapyPathologyClinical trial

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Year
2020
Type
article
Volume
21
Issue
10
Pages
1353-1365
Citations
2300
Access
Closed

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Aurélien Marabelle, Marwan Fakih, Juanita Lopez et al. (2020). Association of tumour mutational burden with outcomes in patients with advanced solid tumours treated with pembrolizumab: prospective biomarker analysis of the multicohort, open-label, phase 2 KEYNOTE-158 study. The Lancet Oncology , 21 (10) , 1353-1365. https://doi.org/10.1016/s1470-2045(20)30445-9

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DOI
10.1016/s1470-2045(20)30445-9