Abstract

Improved understanding of the molecular biology and genetics of bladder cancer has evolved the way localized and advanced disease is diagnosed and treated. While intravesical BCG has remained the mainstay of therapy for intermediate and high-risk non-muscle-invasive bladder cancer, the therapeutic options for muscle-invasive and advanced disease has expanded to include immunotherapy with checkpoint inhibition, targeted therapies, and antibody-drug conjugates.

Keywords

MedicineBladder cancerCystoscopyCystectomyMalignancyCancerDiseaseOncologyRadiation therapyPopulationImmunotherapyInternal medicineUrinary system

MeSH Terms

AdministrationIntravesicalAntineoplastic AgentsBCG VaccineCombined Modality TherapyCystectomyCystoscopyFemaleHumansImmunotherapyMaleMutationNeoplasm InvasivenessRisk FactorsUrinary BladderUrinary Bladder Neoplasms

Affiliated Institutions

Related Publications

Publication Info

Year
2020
Type
review
Volume
324
Issue
19
Pages
1980-1980
Citations
1621
Access
Closed

Social Impact

Altmetric
PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

1621
OpenAlex
45
Influential
1307
CrossRef

Cite This

Andrew T. Lenis, Patrick M. Lec, Karim Chamie et al. (2020). Bladder Cancer. JAMA , 324 (19) , 1980-1980. https://doi.org/10.1001/jama.2020.17598

Identifiers

DOI
10.1001/jama.2020.17598
PMID
33201207

Data Quality

Data completeness: 81%