Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure

2020 New England Journal of Medicine 4,558 citations

Abstract

Among patients receiving recommended therapy for heart failure, those in the empagliflozin group had a lower risk of cardiovascular death or hospitalization for heart failure than those in the placebo group, regardless of the presence or absence of diabetes. (Funded by Boehringer Ingelheim and Eli Lilly; EMPEROR-Reduced ClinicalTrials.gov number, NCT03057977.).

Keywords

EmpagliflozinHeart failureMedicineEjection fractionCardiologyDiabetes mellitusInternal medicineBenzhydryl compoundsBroad spectrumHeart failure with preserved ejection fractionType 2 diabetesEndocrinologyChemistry

Affiliated Institutions

Related Publications

Publication Info

Year
2020
Type
article
Volume
383
Issue
15
Pages
1413-1424
Citations
4558
Access
Closed

External Links

Social Impact

Social media, news, blog, policy document mentions

Citation Metrics

4558
OpenAlex

Cite This

Milton Packer, Stefan D. Anker, Javed Butler et al. (2020). Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure. New England Journal of Medicine , 383 (15) , 1413-1424. https://doi.org/10.1056/nejmoa2022190

Identifiers

DOI
10.1056/nejmoa2022190