Abstract
Maintenance of a reduced or elevated body weight is associated with compensatory changes in energy expenditure, which oppose the maintenance of a body weight that is different from the usual weight. These compensatory changes may account for the poor long-term efficacy of treatments for obesity.
Keywords
Energy expenditureMedicineWeight lossObesityBody weightEnergy metabolismResting energy expenditureInternal medicineEndocrinology
Affiliated Institutions
Related Publications
Obesity and hypertension: long-term effects of weight reduction on blood pressure.
Long-term follow-up studies were conducted on massively obese hypertensive subjects during and after a successful protein supplemented fast (PSMF) in order to correlate blood pr...
The Response to Long-Term Overfeeding in Identical Twins
We undertook this study to determine whether there are differences in the responses of different persons to long-term overfeeding and to assess the possibility that genotypes ar...
Long-Term Effects of Weight Loss and Dietary Sodium Reduction on Incidence of Hypertension
Abstract —To examine the long-term effects of weight loss and dietary sodium reduction on the incidence of hypertension, we studied 181 men and women who participated in the Tri...
Weight-Reducing Effects of the Plasma Protein Encoded by the <i>obese</i> Gene
The gene product of the ob locus is important in the regulation of body weight. The ob product was shown to be present as a 16-kilodalton protein in mouse and human plasma but w...
The Finnish Diabetes Prevention Study (DPS)
OBJECTIVE—To describe the 1) lifestyle intervention used in the Finnish Diabetes Prevention Study, 2) short- and long-term changes in diet and exercise behavior, and 3) effect o...
Publication Info
- Year
- 1995
- Type
- article
- Volume
- 332
- Issue
- 10
- Pages
- 621-628
- Citations
- 1969
- Access
- Closed
External Links
Social Impact
Altmetric
PlumX Metrics
Social media, news, blog, policy document mentions
Citation Metrics
1969
OpenAlex
Cite This
Rudolph L. Leibel,
Michael Rosenbaum,
Jules Hirsch
(1995).
Changes in Energy Expenditure Resulting from Altered Body Weight.
New England Journal of Medicine
, 332
(10)
, 621-628.
https://doi.org/10.1056/nejm199503093321001
Identifiers
- DOI
- 10.1056/nejm199503093321001