Colocalization of Inflammatory Response with B7-H1 Expression in Human Melanocytic Lesions Supports an Adaptive Resistance Mechanism of Immune Escape

Abstract

Activated tumor-infiltrating lymphocytes may induce B7-H1 on melanocytes, which suggests adaptive resistance to antitumor immunity.

Keywords

Immune systemMelanomaAntigenTumor-infiltrating lymphocytesImmunologyCancer researchBiologyColocalizationCytokineInflammationImmunotherapyMedicineCell biology

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Publication Info

Year: 2012
Type: article
Volume: 4
Issue: 127
Pages: 127ra37-127ra37
Citations: 2090
Access: Closed

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APA Style

                            
                                
                                    Janis M. Taube, 
                                
                                    Robert A. Anders, 
                                
                                    Geoffrey D. Young
                                
                                et al.
                            
                            (2012). 
                            Colocalization of Inflammatory Response with B7-H1 Expression in Human Melanocytic Lesions Supports an Adaptive Resistance Mechanism of Immune Escape. 
                            Science Translational Medicine
                            , 4
                            (127)
                            , 127ra37-127ra37.
                            https://doi.org/10.1126/scitranslmed.3003689
                        

Identifiers

DOI: 10.1126/scitranslmed.3003689