Abstract

Abstract The aim of this study was to analyze the clinical data, discharge rate, and fatality rate of COVID‐19 patients for clinical help. The clinical data of COVID‐19 patients from December 2019 to February 2020 were retrieved from four databases. We statistically analyzed the clinical symptoms and laboratory results of COVID‐19 patients and explained the discharge rate and fatality rate with a single‐arm meta‐analysis. The available data of 1994 patients in 10 literatures were included in our study. The main clinical symptoms of COVID‐19 patients were fever (88.5%), cough (68.6%), myalgia or fatigue (35.8%), expectoration (28.2%), and dyspnea (21.9%). Minor symptoms include headache or dizziness (12.1%), diarrhea (4.8%), nausea and vomiting (3.9%). The results of the laboratory showed that the lymphocytopenia (64.5%), increase of C‐reactive protein (44.3%), increase of lactic dehydrogenase (28.3%), and leukocytopenia (29.4%) were more common. The results of single‐arm meta‐analysis showed that the male took a larger percentage in the gender distribution of COVID‐19 patients 60% (95% CI [0.54, 0.65]), the discharge rate of COVID‐19 patients was 52% (95% CI [0.34,0.70]), and the fatality rate was 5% (95% CI [0.01,0.11]).

Keywords

Coronavirus disease 2019 (COVID-19)VirologyCase fatality rate2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)MedicineMeta-analysisEpidemiologyOutbreakInternal medicineInfectious disease (medical specialty)

MeSH Terms

BetacoronavirusBiomarkersC-Reactive ProteinCOVID-19ChinaCoronavirus InfectionsCoughDyspneaFemaleFeverHumansIncidenceLymphopeniaMalePandemicsPatient DischargePneumoniaViralSARS-CoV-2Sex FactorsSurvival Analysis

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Publication Info

Year
2020
Type
review
Volume
92
Issue
6
Pages
577-583
Citations
1530
Access
Closed

Social Impact

Social media, news, blog, policy document mentions

Citation Metrics

1530
OpenAlex
45
Influential

Cite This

Long‐quan Li, Tian Huang, Yongqing Wang et al. (2020). COVID‐19 patients' clinical characteristics, discharge rate, and fatality rate of meta‐analysis. Journal of Medical Virology , 92 (6) , 577-583. https://doi.org/10.1002/jmv.25757

Identifiers

DOI
10.1002/jmv.25757
PMID
32162702
PMCID
PMC7228329

Data Quality

Data completeness: 90%