Abstract
Trommer et al 1 recently reported a patient who experienced focal cerebral ischemia in the postpartum period.They concluded that the changes present on angiography were a manifestation of vasospasm secondary to eclampsia.Brick 2 recently reported a similar case in which a young normotensive woman also experienced focal neurologic deficits in the peripartum period.Angiography revealed a stenotic lesion in the left middle cerebral artery that had resolved by the time of repeat study 11 weeks later.Based on experimental studies 3 -4 demonstrating that female reproductive hormones can induce intimal hyperplasia in experimental animals, it was proposed that the vascular changes in that case were secondary to the direct action of female reproductive steroids on the vessel wall.This may also be the etiology of the angiographically demonstrated "vasospasm" reported in the case of Trommer et al.
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Publication Info
- Year
- 1988
- Type
- letter
- Volume
- 19
- Issue
- 12
- Pages
- 1572-1573
- Citations
- 12
- Access
- Closed
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Identifiers
- DOI
- 10.1161/str.19.12.1572b