Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples

Keywords

Randomized controlled trialLog-rank testClinical trialMedicineSurvival analysisStatistical analysisResearch designMedical physicsStatisticsSurgeryInternal medicine

Affiliated Institutions

Related Publications

Independent prognostic significance of a nuclear proliferation antigen in diffuse large cell lymphomas as determined by the monoclonal antibody Ki-67

TM Grogan , Lippman Sm , CM Spier +5 more

Abstract To assess the prognostic significance of the growth fraction in diffuse large cell lymphoma (DLCL), we studied 105 DLCL patients with the monoclonal antibody Ki-67 appl...

1988 Blood 225 citations

The Magic of Randomization versus the Myth of Real-World Evidence

Rory Collins , Louise Bowman , Martin Landray +1 more

Nonrandomized observational analyses have been promoted as alternatives to randomized clinical trials. However, randomization ensures balance between groups, whereas nonrandomiz...

2020 New England Journal of Medicine 451 citations

1997 Stroke 247 citations

Publication Info

Year: 1977
Type: article
Volume: 35
Issue: 1
Pages: 1-39
Citations: 8389
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

8389

OpenAlex

Cite This

APA Style

                            
                                
                                    Richard Peto, 
                                
                                    M. C. Pike, 
                                
                                    P. Armitage
                                
                                et al.
                            
                            (1977). 
                            Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples. 
                            British Journal of Cancer
                            , 35
                            (1)
                            , 1-39.
                            https://doi.org/10.1038/bjc.1977.1
                        

Identifiers

DOI: 10.1038/bjc.1977.1

Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples

Keywords

Affiliated Institutions

Related Publications

Independent prognostic significance of a nuclear proliferation antigen in diffuse large cell lymphomas as determined by the monoclonal antibody Ki-67

The Magic of Randomization versus the Myth of Real-World Evidence

A Predictive Model for Aggressive Non-Hodgkin's Lymphoma

A Clinical Evaluation of the International Lymphoma Study Group Classification of Non-Hodgkin's Lymphoma

Effect of Antihypertensive Treatment in Patients Having Already Suffered From Stroke

Publication Info

External Links

Social Impact

Citation Metrics

Cite This

Identifiers