Abstract

This report examines prospectively, in the Framingham cohort, the relation of diabetes and impaired glucose tolerance to each of the cardiovascular sequelae, taking into account age, sex, and associated cardiovascular risk factors. The incidence of cardiovascular disease, as well as the levels of cardiovascular risk factors, were found to be higher in diabetic than in nondiabetic men and women. The relative impact of diabetes on coronary heart disease, peripheral vascular disease, or stroke incidence was the same in men and women, but for cardiovascular mortality and cardiac failure the impact is greater for women. Present evidence suggests that alleviation of associated cardiovascular risk factors is the most promising course in reducing cardiovascular sequelae in diabetic patients.

Keywords

MedicineDiabetes mellitusFramingham Risk ScoreFramingham Heart StudyInternal medicineIncidence (geometry)DiseaseImpaired glucose toleranceVascular diseaseCohortCohort studyCardiologyStroke (engine)Type 2 diabetesHeart failureRisk factorEndocrinology

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Publication Info

Year
1979
Type
article
Volume
2
Issue
2
Pages
120-126
Citations
1198
Access
Closed

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W B Kannel, Dan McGee (1979). Diabetes and Glucose Tolerance as Risk Factors for Cardiovascular Disease: The Framingham Study. Diabetes Care , 2 (2) , 120-126. https://doi.org/10.2337/diacare.2.2.120

Identifiers

DOI
10.2337/diacare.2.2.120