Disentangling the relationship between tumor genetic programs and immune responsiveness

Davide Bedognetti; Wouter Hendrickx; Michele Ceccarelli; Lance D. Miller; Barbara Seliger

doi:10.1016/j.coi.2016.02.001

Keywords

Immune systemBiologyPhenotypeChemokineTumor microenvironmentImmunologyCytokineGeneCancer researchGenetics

Affiliated Institutions

Related Publications

Crosstalk between cancer-associated fibroblasts and immune cells in the tumor microenvironment: new findings and future perspectives

Xiaoqi Mao , Jin Xu , Wei Wang +7 more

Cancer-associated fibroblasts (CAFs), a stromal cell population with cell-of-origin, phenotypic and functional heterogeneity, are the most essential components of the tumor micr...

2021 Molecular Cancer 2011 citations

The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints

Nicolás J. Llosa , Michael Cruise , Ada Tam +15 more

Abstract We examined the immune microenvironment of primary colorectal cancer using immunohistochemistry, laser capture microdissection/qRT-PCR, flow cytometry, and functional a...

2014 Cancer Discovery 1398 citations

Molecular profiling to identify relevant immune resistance mechanisms in the tumor microenvironment

Thomas F. Gajewski , Mercedes B. Fuertes , Robbert M. Spaapen +2 more

2010 Current Opinion in Immunology 138 citations

TISIDB: an integrated repository portal for tumor–immune system interactions

Beibei Ru , Ching Ngar Wong , Yin Tong +9 more

Abstract Summary The interaction between tumor and immune system plays a crucial role in both cancer development and treatment response. To facilitate comprehensive investigatio...

2019 Bioinformatics 2506 citations

Inflammation and tumor progression: signaling pathways and targeted intervention

Huakan Zhao , Lei Wu , Guifang Yan +4 more

Cancer development and its response to therapy are regulated by inflammation, which either promotes or suppresses tumor progression, potentially displaying opposing effects on t...

2021 Signal Transduction and Targeted Therapy 2307 citations

Publication Info

Year: 2016
Type: review
Volume: 39
Pages: 150-158
Citations: 50
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Disentangling the relationship between tumor genetic programs and immune responsiveness

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

OpenAlex

Cite This

APA Style

                            
                                    Davide Bedognetti, 
                                
                                    Wouter Hendrickx, 
                                
                                    Michele Ceccarelli
                                
                                et al.
                            
                            (2016). 
                            Disentangling the relationship between tumor genetic programs and immune responsiveness. 
                            Current Opinion in Immunology
                            , 39
                            
                            , 150-158.
                            https://doi.org/10.1016/j.coi.2016.02.001

Identifiers

DOI: 10.1016/j.coi.2016.02.001