Abstract

The dynamics of the attachment of lymphocytes to the endothelium of high endothelial venules in murine Peyer's patches were studied in vivo. Lymphocytes adhered readily to the endothelium lining these vessels, but most of the adhering cells detached within a few seconds. Many lymphocytes, however, experienced multiple collisions with the high endothelial venules, and this substantially increased the efficiency of lymphocyte collection by these vessels.

Keywords

EndotheliumIn vivoHigh endothelial venulesDynamics (music)LymphocyteLymphocyte homing receptorCell biologyBiologyImmunologyEndothelial stem cellPathologyChemistryIn vitroCellCell adhesionMedicineBiochemistryEndocrinologyGenetics

Affiliated Institutions

Related Publications

Endothelial-Leukocyte Adhesion Molecules

One decade ago, vascular endothelium was commonly considered a "non-stick" lining of blood vessels that functioned only to prevent blood coagulation and to separate the vascular...

1993 Annual Review of Immunology 1301 citations

Publication Info

Year
1986
Type
article
Volume
231
Issue
4736
Pages
402-405
Citations
99
Access
Closed

External Links

Social Impact

Social media, news, blog, policy document mentions

Citation Metrics

99
OpenAlex

Cite This

Matthew Bjerknes, Hazel Cheng, Clifford A. Ottaway (1986). Dynamics of Lymphocyte-Endothelial Interactions in Vivo. Science , 231 (4736) , 402-405. https://doi.org/10.1126/science.3941903

Identifiers

DOI
10.1126/science.3941903