Early stroke treatment associated with better outcome

Abstract

If the NINDS rt-PA Stroke Trial treatment protocol is followed, this analysis suggests that patients treated 0 to 90 minutes from stroke onset with rt-PA have an increased odds of improvement at 24 hours and favorable 3-month outcome compared to patients treated later than 90 minutes. No effect of OTT on intracranial hemorrhage was detected within the group treated with rt-PA, possibly due to low power.

Keywords

MedicineConfoundingStroke (engine)Tissue plasminogen activatorUnivariate analysisInternal medicineMultivariate analysisAnesthesia

Affiliated Institutions

National Institute of Neurological Disorders and Stroke US

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Publication Info

Year: 2000
Type: article
Volume: 55
Issue: 11
Pages: 1649-1655
Citations: 862
Access: Closed

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APA Style

                            
                                
                                    John R. Marler, 
                                
                                    Barbara C. Tilley, 
                                
                                    Mei Lü
                                
                                et al.
                            
                            (2000). 
                            Early stroke treatment associated with better outcome. 
                            Neurology
                            , 55
                            (11)
                            , 1649-1655.
                            https://doi.org/10.1212/wnl.55.11.1649
                        

Identifiers

DOI: 10.1212/wnl.55.11.1649