Early versus Standard Antiretroviral Therapy for HIV-Infected Adults in Haiti

Abstract

Early initiation of antiretroviral therapy decreased the rates of death and incident tuberculosis. Access to antiretroviral therapy should be expanded to include all HIV-infected adults who have CD4+ T-cell counts of less than 350 per cubic millimeter, including those who live in areas with limited resources. (ClinicalTrials.gov number, NCT00120510.)

Keywords

MedicineEfavirenzLamivudineZidovudineRegimenHazard ratioConfidence intervalInternal medicineAntiretroviral therapyPediatricsViral loadSurgeryImmunologyHuman immunodeficiency virus (HIV)Viral diseaseVirusHepatitis B virus

MeSH Terms

AIDS-Related Opportunistic InfectionsAdultAnti-Retroviral AgentsAntitubercular AgentsCD4 Lymphocyte CountDrug Administration ScheduleFemaleFollow-Up StudiesHIV InfectionsHaitiHumansKaplan-Meier EstimateMaleMiddle AgedTuberculosisPulmonary

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Publication Info

Year: 2010
Type: article
Volume: 363
Issue: 3
Pages: 257-265
Citations: 374
Access: Closed

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APA Style

                            
                                
                                    Patrice Sévère, 
                                
                                    Marc Antoine Jean Juste, 
                                
                                    Alex Ambroise
                                
                                et al.
                            
                            (2010). 
                            Early versus Standard Antiretroviral Therapy for HIV-Infected Adults in Haiti. 
                            New England Journal of Medicine
                            , 363
                            (3)
                            , 257-265.
                            https://doi.org/10.1056/nejmoa0910370
                        

Identifiers

DOI: 10.1056/nejmoa0910370
PMID: 20647201
PMCID: PMC3676927

Data Quality

Data completeness: 86%