Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly

Abstract

The use of low-dose aspirin as a primary prevention strategy in older adults resulted in a significantly higher risk of major hemorrhage and did not result in a significantly lower risk of cardiovascular disease than placebo. (Funded by the National Institute on Aging and others; ASPREE ClinicalTrials.gov number, NCT01038583 .).

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Affiliated Institutions

• Cleveland Clinic US
• St. Vincent's Hospital KR
• The University of Melbourne AU
• Rush University Medical Center US
• University of Iowa US
• University of Tennessee Health Science Center US
• University of Minnesota US
• Monash Alfred Psychiatry Research centre AU
• Berman Center for Outcomes and Clinical Research US
• The University of Adelaide AU
• Monash University AU
• Curtin University AU
• Florey Institute of Neuroscience and Mental Health AU
• Royal Perth Hospital AU
• National Institute on Aging US
• Hennepin Healthcare Research Institute US
• Australian National University AU
• HealthPartners US
• Baker Heart and Diabetes Institute AU
• Brown University US
• Minnesota State University, Mankato US
• The University of Western Australia AU
• Wake Forest University US
• University of Tasmania AU

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