Effect of Captopril on Mortality and Morbidity in Patients with Left Ventricular Dysfunction after Myocardial Infarction

Abstract

In patients with asymptomatic left ventricular dysfunction after myocardial infarction, long-term administration of captopril was associated with an improvement in survival and reduced morbidity and mortality due to major cardiovascular events. These benefits were observed in patients who received thrombolytic therapy, aspirin, or beta-blockers, as well as those who did not, suggesting that treatment with captopril leads to additional improvement in outcome among selected survivors of myocardial infarction.

Keywords

CaptoprilMedicineMyocardial infarctionCardiologyInternal medicineACE inhibitorVentricular remodelingElectrocardiography in myocardial infarctionAngiotensin-converting enzymeBlood pressure

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Publication Info

Year: 1992
Type: article
Volume: 327
Issue: 10
Pages: 669-677
Citations: 5919
Access: Closed

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APA Style

                            
                                
                                    Marc A. Pfeffer, 
                                
                                    Eugene Braunwald, 
                                
                                    Lemuel A. Moyé
                                
                                et al.
                            
                            (1992). 
                            Effect of Captopril on Mortality and Morbidity in Patients with Left Ventricular Dysfunction after Myocardial Infarction. 
                            New England Journal of Medicine
                            , 327
                            (10)
                            , 669-677.
                            https://doi.org/10.1056/nejm199209033271001
                        

Identifiers

DOI: 10.1056/nejm199209033271001