Effect of ceramide N-acyl chain and polar headgroup structure on the properties of ordered lipid domains (lipid rafts)

Megha Megha; Peter Sawatzki; Thomas Kolter; Robert Bittman; Erwin London

doi:10.1016/j.bbamem.2007.05.007

Keywords

CeramideSphingomyelinSphingolipidRaftLipid raftChemistryVesicleSterolLipid microdomainBiochemistryMembraneCholesterolOrganic chemistry

Affiliated Institutions

Related Publications

FUNCTIONS OF LIPID RAFTS IN BIOLOGICAL MEMBRANES

Deborah A. Brown , Erwin London

▪ Abstract Recent studies showing that detergent-resistant membrane fragments can be isolated from cells suggest that biological membranes are not always in a liquid-crystalline...

1998 Annual Review of Cell and Development... 2929 citations

Role of Lipid Modifications in Targeting Proteins to Detergent-resistant Membrane Rafts

Karin Melkonian , Anne G. Ostermeyer , Zhe Chen +2 more

Sphingolipid and cholesterol-rich Triton X-100-insoluble membrane fragments (detergent-resistant membranes, DRMs) containing lipids in a state similar to the liquid-ordered phas...

1999 Journal of Biological Chemistry 624 citations

Ceramide Drives Cholesterol Out of the Ordered Lipid Bilayer Phase into the Crystal Phase in 1-Palmitoyl-2-oleoyl-<i>sn</i>-glycero-3-phosphocholine/Cholesterol/Ceramide Ternary Mixtures

Md Rejwan Ali , Kwan Hon Cheng , Juyang Huang

The effect of brain ceramide on the maximum solubility of cholesterol in ternary mixtures of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC), cholesterol, and ceramide w...

2006 Biochemistry 75 citations

Detergent-insoluble glycosphingolipid/cholesterol-rich membrane domains, lipid rafts and caveolae (Review)

Nigel M. Hooper

Within the cell membrane glycosphingolipids and cholesterol cluster together in distinct domains or lipid rafts, along with glycosyl-phosphatidylinositol (GPI)-anchored proteins...

1999 Molecular Membrane Biology 388 citations

Interaction of cholesterol with various glycerophospholipids and sphingomyelin

M. B. Sankaram , T. E. Thompson

The influence of cholesterol on the phase behavior of glycerophospholipids and sphingomyelins was investigated by spin-label electron spin resonance (ESR) spectroscopy. 4-(4,4-D...

1990 Biochemistry 311 citations

Publication Info

Year: 2007
Type: article
Volume: 1768
Issue: 9
Pages: 2205-2212
Citations: 98
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Effect of ceramide N-acyl chain and polar headgroup structure on the properties of ordered lipid domains (lipid rafts)

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

OpenAlex

Cite This

APA Style

                            
                                
                                    Megha Megha, 
                                
                                    Peter Sawatzki, 
                                
                                    Thomas Kolter
                                
                                et al.
                            
                            (2007). 
                            Effect of ceramide N-acyl chain and polar headgroup structure on the properties of ordered lipid domains (lipid rafts). 
                            Biochimica et Biophysica Acta (BBA) - Biomembranes
                            , 1768
                            (9)
                            , 2205-2212.
                            https://doi.org/10.1016/j.bbamem.2007.05.007
                        

Identifiers

DOI: 10.1016/j.bbamem.2007.05.007