Effect of continuous versus dichotomous outcome variables on study power when sample sizes of orthopaedic randomized trials are small

Mohit Bhandari; Heather V. Lochner; Paul Tornetta

doi:10.1007/s004020100347

Keywords

MedicineSample size determinationRandomized controlled trialOutcome (game theory)Orthopedic surgeryStatistical powerContinuous variableClinical trialPhysical therapyStatisticsSurgeryInternal medicineMathematics

Affiliated Institutions

Related Publications

Detection of Atrial Fibrillation After Ischemic Stroke or Transient Ischemic Attack

Amit K Kishore , Andy Vail , Arshad Majid +4 more

Background and Purpose— Atrial fibrillation (AF) confers a high risk of recurrent stroke, although detection methods and definitions of paroxysmal AF during screening vary. We t...

2014 Stroke 366 citations

Evaluating surrogate markers.

Michael D. Hughes , Victor DeGruttola , Seth L. Welles

We discuss approaches for efficiently evaluating potential surrogate markers; in particular, we focus on case-cohort designs in which marker evaluation is undertaken only for a ...

1995 PubMed 29 citations

Chemotherapy in Advanced Gastric Cancer: A Systematic Review and Meta-Analysis Based on Aggregate Data

Dorothea Wagner , Wilfried Grothe , Johannes Haerting +3 more

Purpose This systematic review and meta-analysis were performed to assess the efficacy and tolerability of chemotherapy in patients with advanced gastric cancer. Methods Randomi...

2006 Journal of Clinical Oncology 1179 citations

Chemotherapy in adult high-grade glioma: a systematic review and meta-analysis of individual patient data from 12 randomised trials

Lesley Stewart

Trials on the effect of systemic chemotherapy on survival and recurrence in adults with high-grade glioma have had inconclusive results. We undertook a systematic review and met...

2002 The Lancet 1221 citations

European Association of Urology Guidelines on Renal Cell Carcinoma: The 2019 Update

Börje Ljungberg , Laurence Albigès , Yasmin Abu‐Ghanem +16 more

The European Association of Urology Renal Cell Carcinoma (RCC) Guideline Panel has prepared evidence-based guidelines and recommendations for the management of RCC. To provide a...

2019 European Urology 1486 citations

Publication Info

Year: 2002
Type: article
Volume: 122
Issue: 2
Pages: 96-98
Citations: 60
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Effect of continuous versus dichotomous outcome variables on study power when sample sizes of orthopaedic randomized trials are small

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

OpenAlex

Cite This

APA Style

                            
                                    Mohit Bhandari, 
                                
                                    Heather V. Lochner, 
                                
                                    Paul Tornetta
                                
                            (2002). 
                            Effect of continuous versus dichotomous outcome variables on study power when sample sizes of orthopaedic randomized trials are small. 
                            Archives of Orthopaedic and Trauma Surgery
                            , 122
                            (2)
                            , 96-98.
                            https://doi.org/10.1007/s004020100347

Identifiers

DOI: 10.1007/s004020100347