Abstract

The angiotensin-converting--enzyme inhibitor enalapril significantly reduced the incidence of heart failure and the rate of related hospitalizations, as compared with the rates in the group given placebo, among patients with asymptomatic left ventricular dysfunction. There was also a trend toward fewer deaths due to cardiovascular causes among the patients who received enalapril.

Keywords

EnalaprilMedicineHeart failureAsymptomaticPlaceboInternal medicineConfidence intervalEjection fractionCardiologyACE inhibitorAngiotensin-converting enzymeSurgeryBlood pressure

Related Publications

Publication Info

Year
1992
Type
article
Volume
327
Issue
10
Pages
685-691
Citations
3728
Access
Closed

External Links

Citation Metrics

3728
OpenAlex

Cite This

Salim Yusuf, Bertram Pitt, C.E. Davis et al. (1992). Effect of Enalapril on Mortality and the Development of Heart Failure in Asymptomatic Patients with Reduced Left Ventricular Ejection Fractions. New England Journal of Medicine , 327 (10) , 685-691. https://doi.org/10.1056/nejm199209033271003

Identifiers

DOI
10.1056/nejm199209033271003