Abstract

There have been no high quality experimental trials looking at control policies for meningococcal disease. The best available evidence is from retrospective studies. The risk of meningococcal disease in household contacts of a patient can be reduced by an estimated 89% if they take antibiotics known to eradicate meningococcal carriage. Chemoprophylaxis should be recommended for the index patient and all household contacts.

Keywords

ChemoprophylaxisMedicineMeningococcal diseaseConfidence intervalObservational studyMeta-analysisPediatricsDiseaseNeisseria meningitidisRandomized controlled trialCarriageRelative riskRate ratioSystematic reviewInternal medicineMEDLINEIntensive care medicinePathology

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Publication Info

Year
2004
Type
review
Volume
328
Issue
7452
Pages
1339-1339
Citations
75
Access
Closed

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Bernadette Purcell, S Samuelsson, Susan Hahné et al. (2004). Effectiveness of antibiotics in preventing meningococcal disease after a case: systematic review. BMJ , 328 (7452) , 1339-1339. https://doi.org/10.1136/bmj.328.7452.1339

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DOI
10.1136/bmj.328.7452.1339