Abstract
The ovulatory response to clomiphene can be increased in obese women with the polycystic ovary syndrome by decreasing insulin secretion with metformin.
Keywords
Polycystic ovaryMetforminMedicineOvulationEndocrinologyInternal medicineOvulation inductionOvaryInsulinInsulin resistanceHormone
MeSH Terms
AdultClomipheneFemaleFertility AgentsFemaleHumansHyperinsulinismHypoglycemic AgentsMetforminObesityOvulationOvulation InductionPolycystic Ovary Syndrome
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Publication Info
- Year
- 1998
- Type
- article
- Volume
- 338
- Issue
- 26
- Pages
- 1876-1880
- Citations
- 786
- Access
- Closed
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Cite This
John E. Nestler,
Daniela Jakubowicz,
William S. Evans
et al.
(1998).
Effects of Metformin on Spontaneous and Clomiphene-Induced Ovulation in the Polycystic Ovary Syndrome.
New England Journal of Medicine
, 338
(26)
, 1876-1880.
https://doi.org/10.1056/nejm199806253382603
Identifiers
- DOI
- 10.1056/nejm199806253382603
- PMID
- 9637806