Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes

Christopher P. Cannon; Michael A. Blazing; Robert P. Giugliano; Amy McCagg; Jennifer A. White; Pierre Théroux; Harald Darius; Basil S. Lewis; Ton Oude Ophuis; J. Wouter Jukema; Gaetano Maria De Ferrari; Witold Rużyłło; Paul De Lucca; Canqing Yu; Erin A. Bohula; Martin Craig; Stephen D. Wiviott; Andrew M. Tershakovec; Ming‐Shyan Lin; Eugene Braunwald; Robert M. Califf

doi:10.1056/nejmoa1410489

Abstract

When added to statin therapy, ezetimibe resulted in incremental lowering of LDL cholesterol levels and improved cardiovascular outcomes. Moreover, lowering LDL cholesterol to levels below previous targets provided additional benefit. (Funded by Merck; IMPROVE-IT ClinicalTrials.gov number, NCT00202878.).

Keywords

EzetimibeMedicineAcute coronary syndromeStatinCardiologyInternal medicineMyocardial infarction

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Publication Info

Year: 2015
Type: article
Volume: 372
Issue: 25
Pages: 2387-2397
Citations: 4172
Access: Closed

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APA Style

                            
                                
                                    Christopher P. Cannon, 
                                
                                    Michael A. Blazing, 
                                
                                    Robert P. Giugliano
                                
                                et al.
                            
                            (2015). 
                            Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes. 
                            New England Journal of Medicine
                            , 372
                            (25)
                            , 2387-2397.
                            https://doi.org/10.1056/nejmoa1410489
                        

Identifiers

DOI: 10.1056/nejmoa1410489