Ferroptosis in cancer therapy: a novel approach to reversing drug resistance

Chen Zhang; Xinyin Liu; Shidai Jin; Yi Chen; Renhua Guo

doi:10.1186/s12943-022-01530-y

Keywords

ReversingDrug resistanceCancerAutophagyCancer researchBiologyImmunotherapyCancer cellDrugCancer therapyChemotherapeutic drugsImmunologyApoptosisPharmacology

Affiliated Institutions

Related Publications

Mechanisms of Multidrug Resistance in Cancer Chemotherapy

Karol Bukowski , Mateusz Kciuk , Renata Kontek

Cancer is one of the main causes of death worldwide. Despite the significant development of methods of cancer healing during the past decades, chemotherapy still remains the mai...

2020 International Journal of Molecular Sc... 1583 citations

Specific P53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients

Turid Aas , Anne‐Lise Børresen , Stephanie Geisler +5 more

The mechanisms causing resistance to chemotherapeutic drugs in cancer patients are poorly understood. Recent evidence suggests that different forms of chemotherapy may exert the...

1996 Nature Medicine 736 citations

Ferroptosis: mechanisms and links with diseases

Hong-Fa Yan , Ting Zou , Qing‐zhang Tuo +4 more

2021 Signal Transduction and Targeted Therapy 1254 citations

A view on drug resistance in cancer

Neil Vasan , José Baselga , David M. Hyman

The problem of resistance to therapy in cancer is multifaceted. Here we take a reductionist approach to define and separate the key determinants of drug resistance, which includ...

2019 Nature 2484 citations

Cyclooxygenase-2: Potential Role in Regulation of Drug Efflux and Multidrug Resistance Phenotype

Andrey Sorokin

Multidrug resistance (MDR) of cancer cells to cytostatic agents is the major obstacle for the succesfull chemotherapy. One of the causes of the development of cellular resistanc...

2004 Current Pharmaceutical Design 83 citations

Publication Info

Year: 2022
Type: review
Volume: 21
Issue: 1
Pages: 47-47
Citations: 1149
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Ferroptosis in cancer therapy: a novel approach to reversing drug resistance

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

1149

OpenAlex

Cite This

APA Style

                            
                                
                                    Chen Zhang, 
                                
                                    Xinyin Liu, 
                                
                                    Shidai Jin
                                
                                et al.
                            
                            (2022). 
                            Ferroptosis in cancer therapy: a novel approach to reversing drug resistance. 
                            Molecular Cancer
                            , 21
                            (1)
                            , 47-47.
                            https://doi.org/10.1186/s12943-022-01530-y
                        

Identifiers

DOI: 10.1186/s12943-022-01530-y