Abstract
Electrostatic interactions play an important role in nanofluidic channels when the channel size is comparable to the Debye screening length. Electrostatic fields have been used to control concentration and transport of ions in nanofluidic transistors. Here, we report a transistor-reservoir-transistor circuit that can be used to turn “on” or “off” protein transport using electrostatic fields with gate voltages of ±1V. Our results suggest that global electrostatic interactions of the protein were dominant over other interactions in the nanofluidic transistor. The fabrication technique also demonstrates the feasibility of nanofluidic integrated circuits for the manipulation of biomolecules in picoliter volumes.
Keywords
TransistorDebye lengthField-effect transistorElectrostaticsNanotechnologyNanofluidicsFabricationMaterials scienceNanoelectronicsElectronic circuitVoltageBiomoleculeOptoelectronicsChemistryElectrical engineeringIonEngineering
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Publication Info
- Year
- 2006
- Type
- article
- Volume
- 88
- Issue
- 12
- Citations
- 194
- Access
- Closed
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Cite This
Rohit Karnik,
Kenneth Castelino,
Arun Majumdar
(2006).
Field-effect control of protein transport in a nanofluidic transistor circuit.
Applied Physics Letters
, 88
(12)
.
https://doi.org/10.1063/1.2186967
Identifiers
- DOI
- 10.1063/1.2186967