Abstract
This review summarizes the clinical, imaging, and pathological features of frontotemporal dementia (FTD). Clinicians have become increasingly sensitive to FTD in the differential diagnosis of Alzheimer's disease. Clinical subgroups of FTD patients have been recognized, including patients with progressive non-fluent aphasia, semantic dementia, and behavioral disorder with executive difficulty. The clinical, neuroimaging and neuropathological profiles associated with these clinically defined subgroups are examined. ( JINS , 2002, 8 , 566–583.)
Keywords
Frontotemporal dementiaSemantic dementiaPrimary progressive aphasiaNeuroimagingDementiaAphasiaPathologicalDifferential diagnosisFrontotemporal lobar degenerationPsychologyDiseaseMedicinePsychiatryPathology
MeSH Terms
AgedAphasiaCognition DisordersDementiaFrontal LobeHumansNeuropsychological TestsSemanticsSeverity of Illness IndexTemporal Lobe
Affiliated Institutions
Related Publications
Clinicopathological correlates in frontotemporal dementia
Abstract The term frontotemporal dementia (FTD) encompasses a range of clinical syndromes that are believed not to map reliably onto the spectrum of recognized pathologies. This...
Histopathological changes underlying frontotemporal lobar degeneration with clinicopathological correlation
We have investigated the pathological correlates of dementia in the brains from a consecutive series of 70 patients dying with a clinical diagnosis of frontotemporal lobar degen...
Frontotemporal lobar degeneration with motor neuron disease-type inclusions predominates in 76 cases of frontotemporal degeneration
This report presents the largest series of consecutive, neuropathologically confirmed cases of frontotemporal degeneration (FTD). Prior studies have found dementia lacking disti...
Frontotemporal dementia: Clinicopathological correlations
Abstract Objective Frontotemporal lobar degeneration (FTLD) is characterized by impairments in social, behavioral, and/or language function, but postmortem studies indicate that...
Clinical and Pathological Diagnosis of Frontotemporal Dementia
An international group of clinical and basic scientists participated in the Frontotemporal Dementia and Pick's Disease Criteria Conference at the National Institutes of Health i...
Publication Info
- Year
- 2002
- Type
- review
- Volume
- 8
- Issue
- 4
- Pages
- 566-583
- Citations
- 186
- Access
- Closed
External Links
Social Impact
Altmetric
PlumX Metrics
Social media, news, blog, policy document mentions
Citation Metrics
186
OpenAlex
8
Influential
126
CrossRef
Cite This
Murray Grossman
(2002).
Frontotemporal dementia: A review.
Journal of the International Neuropsychological Society
, 8
(4)
, 566-583.
https://doi.org/10.1017/s1355617702814357
Identifiers
- DOI
- 10.1017/s1355617702814357
- PMID
- 12030310