Gene-Expression Profiles in Hereditary Breast Cancer

Abstract

Significantly different groups of genes are expressed by breast cancers with BRCA1 mutations and breast cancers with BRCA2 mutations. Our results suggest that a heritable mutation influences the gene-expression profile of the cancer.

Keywords

Breast cancerGeneMutationGenotypeBRCA2 ProteinCancerCancer researchGeneticsBiologyMedicineGermline mutation

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Publication Info

Year: 2001
Type: letter
Volume: 344
Issue: 8
Pages: 539-548
Citations: 1733
Access: Closed

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APA Style

                            
                                
                                    Ingrid Hedenfalk, 
                                
                                    David Duggan, 
                                
                                    Y Chen
                                
                                et al.
                            
                            (2001). 
                            Gene-Expression Profiles in Hereditary Breast Cancer. 
                            New England Journal of Medicine
                            , 344
                            (8)
                            , 539-548.
                            https://doi.org/10.1056/nejm200102223440801
                        

Identifiers

DOI: 10.1056/nejm200102223440801