Gene regulation by long non-coding RNAs and its biological functions

Keywords

BiologyBiogenesisChromatinGeneRegulation of gene expressionGene expressionComputational biologyTranslation (biology)Long non-coding RNASubcellular localizationFunction (biology)Ribosome biogenesisRNACell biologyChromatin remodelingGeneticsRibosomeMessenger RNA

Affiliated Institutions

Related Publications

Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation

Jacob A. O’Brien , Heyam Hayder , Yara Zayed +1 more

MicroRNAs (miRNAs) are a class of non-coding RNAs that play important roles in regulating gene expression. The majority of miRNAs are transcribed from DNA sequences into primary...

2018 Frontiers in Endocrinology 4825 citations

The biogenesis, biology and characterization of circular RNAs

Lasse S. Kristensen , Maria Schertz Andersen , Lotte Victoria Winther Stagsted +3 more

2019 Nature Reviews Genetics 5128 citations

U1 snRNP regulates cancer cell migration and invasion in vitro

Jung‐Min Oh , Christopher C. Venters , Chao Di +8 more

Abstract Stimulated cells and cancer cells have widespread shortening of mRNA 3’-untranslated regions (3’UTRs) and switches to shorter mRNA isoforms due to usage of more proxima...

2020 Nature Communications 7100 citations

NCBI Epigenomics: a new public resource for exploring epigenomic data sets

Ian M. Fingerman , Latisha McDaniel , Xiaoqing Zhang +5 more

The Epigenomics database at the National Center for Biotechnology Information (NCBI) is a new resource that has been created to serve as a comprehensive public resource for whol...

2010 Nucleic Acids Research 66 citations

A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial–mesenchymal transition

Manuel Beltrán , Isabel Puig , Cristina Peña +5 more

Expression of Snail1 in epithelial cells triggers an epithelial–mesenchymal transition (EMT). Here, we demonstrate that the synthesis of Zeb2, a transcriptional repressor of E-c...

2008 Genes & Development 669 citations

Publication Info

Year: 2020
Type: review
Volume: 22
Issue: 2
Pages: 96-118
Citations: 4643
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Gene regulation by long non-coding RNAs and its biological functions

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

4643

OpenAlex

Cite This

APA Style

                            
                                
                                    Luisa Statello, 
                                
                                    Chunjie Guo, 
                                
                                    Ling‐Ling Chen
                                
                                et al.
                            
                            (2020). 
                            Gene regulation by long non-coding RNAs and its biological functions. 
                            Nature Reviews Molecular Cell Biology
                            , 22
                            (2)
                            , 96-118.
                            https://doi.org/10.1038/s41580-020-00315-9
                        

Identifiers

DOI: 10.1038/s41580-020-00315-9