Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Brian W. Kunkle , Benjamin Grenier‐Boley , Rebecca Sims , Brian W. Kunkle , Benjamin Grenier‐Boley , Rebecca Sims , Joshua C. Bis , Vincent Damotte , Adam C. Naj , Anne Boland , Maria Vronskaya , Sven J. van der Lee , Alexandre Amlie‐Wolf , Céline Bellenguez , Aura Frizatti , Vincent Chouraki , Eden R. Martin , Kristel Sleegers , Nandini Badarinarayan , Jóhanna Jakobsdóttir , Kara L. Hamilton‐Nelson , Sonia Moreno–Grau , Robert Olaso , Rachel Raybould , Yuning Chen , Amanda B Kuzma , Mikko Hiltunen , Taniesha Morgan , Shahzad Ahmad , Badri N. Vardarajan , Jacques Epelbaum , Per Hoffmann , Merçé Boada , Gary W. Beecham , Jean-Guillaume Garnier , Denise Harold , Annette L. Fitzpatrick , Otto Valladares , Marie-Laure Moutet , Amy Gerrish , Albert V. Smith , Liming Qu , Delphine Bacq , Nicola Denning , Xueqiu Jian , Yi Zhao , Maria Del Zompo , Nick C. Fox , Seung‐Hoan Choi , Ignacio Mateo , Joseph T. Hughes , Hieab H.H. Adams , John Malamon , Florentino Sánchez-García , Yogen Patel , Jennifer A. Brody , Beth A. Dombroski , María Cándida Déniz Naranjo , Makrina Daniilidou , Guðný Eiríksdóttir , Shubhabrata Mukherjee , David Wallon , James Uphill , Thor Aspelund , Laura B. Cantwell , Fabienne Garzia , Daniela Galimberti , Edith Hofer , Mariusz Butkiewicz , Bertrand Fin , Elio Scarpini , Chloé Sarnowski , William S. Bush , Stéphane Meslage , Johannes Kornhuber , Charles C. White , Yeunjoo E. Song , Robert C. Barber , Sebastiaan Engelborghs , Sabrina Sordon , Dina Voijnovic , Perrie M. Adams , Rik Vandenberghe , Manuel Mayhaus , L. Adrienne Cupples , Marilyn S. Albert , Peter Paul De Deyn , Wei Gu , J.J. Himali , Duane Beekly , Alessio Squassina , Annette M. Hartmann , Adelina Orellana , Deborah Blacker , Eloy Rodríguez‐Rodríguez , Simon Lovestone , Melissa E. Garcia , Rachelle S. Doody , Carmen Munoz-Fernadez , Rebecca Sussams , Honghuang Lin , Thomas Fairchild , Yolanda A. Benito
2019 Nature Genetics 2,968 citations

Keywords

BiologyImmunityDiseaseGeneticsAlzheimer's diseaseMeta-analysisBioinformaticsEvolutionary biologyComputational biologyImmune systemInternal medicine

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Year
2019
Type
review
Volume
51
Issue
3
Pages
414-430
Citations
2968
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Brian W. Kunkle, Benjamin Grenier‐Boley, Rebecca Sims et al. (2019). Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics , 51 (3) , 414-430. https://doi.org/10.1038/s41588-019-0358-2

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DOI
10.1038/s41588-019-0358-2