Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences

Fernando O. Martínez; Laura Helming; Ronny Milde; Audrey Varin; Barbro N. Melgert; Christina Draijer; Benjamin Thomas; Marco Fabbri; Anjali Crawshaw; Ling‐Pei Ho; Nick H.T. ten Hacken; Viviana Cobos Jiménez; Neeltje A. Kootstra; Jörg Hamann; David R. Greaves; Massimo Locati; Alberto Mantovani; Siamon Gordon

doi:10.1182/blood-2012-06-436212

Abstract

Key Points Human and mouse macrophages share partially conserved gene and protein expression programs in the resting or M2 activated state. TGM2 is a novel M2 marker consistently induced in human and mouse M2 macrophages.

Keywords

BiologyImmunologyMolecular biologyGeneticsMedicine

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Publication Info

Year: 2013
Type: article
Volume: 121
Issue: 9
Pages: e57-e69
Citations: 480
Access: Closed

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APA Style

                            
                                
                                    Fernando O. Martínez, 
                                
                                    Laura Helming, 
                                
                                    Ronny Milde
                                
                                et al.
                            
                            (2013). 
                            Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences. 
                            Blood
                            , 121
                            (9)
                            , e57-e69.
                            https://doi.org/10.1182/blood-2012-06-436212
                        

Identifiers

DOI: 10.1182/blood-2012-06-436212