Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations

Keywords

BiologyDiseaseGeneticsMultifactorial InheritancePopulationPolygenic risk scoreCoronary artery diseaseBioinformaticsInternal medicineMedicineGeneSingle-nucleotide polymorphismGenotype

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Publication Info

Year: 2018
Type: article
Volume: 50
Issue: 9
Pages: 1219-1224
Citations: 2836
Access: Closed

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APA Style

                            
                                
                                    Amit V. Khera, 
                                
                                    Mark Chaffin, 
                                
                                    Krishna G. Aragam
                                
                                et al.
                            
                            (2018). 
                            Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations. 
                            Nature Genetics
                            , 50
                            (9)
                            , 1219-1224.
                            https://doi.org/10.1038/s41588-018-0183-z
                        

Identifiers

DOI: 10.1038/s41588-018-0183-z