Abstract

Abstract This article provides a status report on the global burden of cancer worldwide using the GLOBOCAN 2018 estimates of cancer incidence and mortality produced by the International Agency for Research on Cancer, with a focus on geographic variability across 20 world regions. There will be an estimated 18.1 million new cancer cases (17.0 million excluding nonmelanoma skin cancer) and 9.6 million cancer deaths (9.5 million excluding nonmelanoma skin cancer) in 2018. In both sexes combined, lung cancer is the most commonly diagnosed cancer (11.6% of the total cases) and the leading cause of cancer death (18.4% of the total cancer deaths), closely followed by female breast cancer (11.6%), prostate cancer (7.1%), and colorectal cancer (6.1%) for incidence and colorectal cancer (9.2%), stomach cancer (8.2%), and liver cancer (8.2%) for mortality. Lung cancer is the most frequent cancer and the leading cause of cancer death among males, followed by prostate and colorectal cancer (for incidence) and liver and stomach cancer (for mortality). Among females, breast cancer is the most commonly diagnosed cancer and the leading cause of cancer death, followed by colorectal and lung cancer (for incidence), and vice versa (for mortality); cervical cancer ranks fourth for both incidence and mortality. The most frequently diagnosed cancer and the leading cause of cancer death, however, substantially vary across countries and within each country depending on the degree of economic development and associated social and life style factors. It is noteworthy that high‐quality cancer registry data, the basis for planning and implementing evidence‐based cancer control programs, are not available in most low‐ and middle‐income countries. The Global Initiative for Cancer Registry Development is an international partnership that supports better estimation, as well as the collection and use of local data, to prioritize and evaluate national cancer control efforts. CA: A Cancer Journal for Clinicians 2018;0:1‐31. © 2018 American Cancer Society

Keywords

CancerColorectal cancerMedicineSkin cancerBreast cancerProstate cancerLung cancerLiver cancerStomach cancerCauses of cancerIncidence (geometry)Cancer registryCause of deathEpidemiology of cancerMortality rateOncologyInternal medicineDisease

MeSH Terms

AdolescentAdultAge DistributionAgedAged80 and overCause of DeathChildChildPreschoolFemaleGlobal Burden of DiseaseGlobal HealthHumansIncidenceInfantInfantNewbornMaleMiddle AgedNeoplasmsPrevalenceRegistriesRisk FactorsSex DistributionSurvival RateYoung Adult

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Publication Info

Year
2018
Type
article
Volume
68
Issue
6
Pages
394-424
Citations
86148
Access
Closed

Social Impact

Social media, news, blog, policy document mentions

Citation Metrics

86148
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3315
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Cite This

Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram et al. (2018). Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA A Cancer Journal for Clinicians , 68 (6) , 394-424. https://doi.org/10.3322/caac.21492

Identifiers

DOI
10.3322/caac.21492
PMID
30207593

Data Quality

Data completeness: 86%