High-frequency network oscillation in the hippocampus

Abstract

Pyramidal cells in the CA1 hippocampal region displayed transient network oscillations (200 hertz) during behavioral immobility, consummatory behaviors, and slow-wave sleep. Simultaneous, multisite recordings revealed temporal and spatial coherence of neuronal activity during population oscillations. Participating pyramidal cells discharged at a rate lower than the frequency of the population oscillation, and their action potentials were phase locked to the negative phase of the simultaneously recorded oscillatory field potentials. In contrast, interneurons discharged at population frequency during the field oscillations. Thus, synchronous output of cooperating CA1 pyramidal cells may serve to induce synaptic enhancement in target structures of the hippocampus.

Keywords

Hippocampal formationNeuroscienceHippocampusOscillation (cell signaling)Pyramidal cellPopulationCoherence (philosophical gambling strategy)PhysicsLocal field potentialPsychologyChemistryMedicine

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Publication Info

Year: 1992
Type: article
Volume: 256
Issue: 5059
Pages: 1025-1027
Citations: 1232
Access: Closed

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APA Style

                            
                                
                                    György Buzsáki, 
                                
                                    Zsolt Horváth, 
                                
                                    Ronald Urioste
                                
                                et al.
                            
                            (1992). 
                            High-frequency network oscillation in the hippocampus. 
                            Science
                            , 256
                            (5059)
                            , 1025-1027.
                            https://doi.org/10.1126/science.1589772
                        

Identifiers

DOI: 10.1126/science.1589772