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De novo methylation of the MyoD1 CpG island during the establishment of immortal cell lines.
CpG dinucleotides are unevenly distributed in the vertebrate genome. Bulk DNA is depleted of CpGs and most of the cytosines in the dinucleotide in this fraction are methylated. ...
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia.
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Dnmt2 is not required for de novo and maintenance methylation of viral DNA in embryonic stem cells
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De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells
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Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains
There is a growing realization that some aging-associated phenotypes/diseases have an epigenetic basis. Here, we report the first genome-scale study of epigenomic dynamics durin...
Publication Info
- Year
- 1990
- Type
- article
- Volume
- 62
- Issue
- 3
- Pages
- 503-514
- Citations
- 705
- Access
- Closed
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Identifiers
- DOI
- 10.1016/0092-8674(90)90015-7