Abstract

Among the proposed techniques for delivering drugs to specific locations within the human body, magnetic drug targeting surpasses due to its non-invasive character and its high targeting efficiency. Although the method has been proposed almost 30 years ago, the technical problems obstruct possible applications. It is the aim of the present work to classify the emerging problems and propose satisfactory answers. A general phenomenological theory is developed and a model case is studied, which incorporates all the physical parameters of the problem.

Keywords

Character (mathematics)Computer scienceRisk analysis (engineering)Targeted drug deliveryWork (physics)DrugManagement scienceBiochemical engineeringMedicineEngineeringMathematicsPharmacologyMechanical engineering

MeSH Terms

Biocompatible MaterialsBlood Flow VelocityCarotid ArteriesComputer SimulationDrug CarriersDrug Delivery SystemsFemoral ArteryHemorheologyMagneticsMicrospheresModelsCardiovascularSensitivity and SpecificityTissue Adhesions

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Publication Info

Year
2002
Type
article
Volume
35
Issue
6
Pages
813-821
Citations
277
Access
Closed

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Cite This

P.A. Voltairas, Dimitrios I. Fotiadis, Lampros K. Michalis (2002). Hydrodynamics of magnetic drug targeting. Journal of Biomechanics , 35 (6) , 813-821. https://doi.org/10.1016/s0021-9290(02)00034-9

Identifiers

DOI
10.1016/s0021-9290(02)00034-9
PMID
12021001

Data Quality

Data completeness: 81%