Abstract
Secreted RNAs share specific sequence motifs that may potentially function as cis-acting elements targeting RNAs to exosomes. Discovery of these motifs will be useful for our understanding the roles of eRNAs in cell-cell communication and genetic reprogramming of the target cells. It will also facilitate nano-scale vesicle engineering and selective targeting of RNAs of interest to these vesicles for gene therapy purposes.
Keywords
ExosomeMicrovesiclesBiologyRNACell biologyNon-coding RNAComputational biologymicroRNASequence motifGeneticsGene
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Publication Info
- Year
- 2011
- Type
- article
- Volume
- 12
- Issue
- Suppl 3
- Pages
- S18-S18
- Citations
- 171
- Access
- Closed
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Cite This
Arsen O. Batagov,
Vladimir A. Kuznetsov,
Igor V. Kurochkin
(2011).
Identification of nucleotide patterns enriched in secreted RNAs as putative cis-acting elements targeting them to exosome nano-vesicles.
BMC Genomics
, 12
(Suppl 3)
, S18-S18.
https://doi.org/10.1186/1471-2164-12-s3-s18
Identifiers
- DOI
- 10.1186/1471-2164-12-s3-s18