Helicobacter pylori Infection and the Development of Gastric Cancer

Naomi Uemura; Shiro Okamoto; Soichiro Yamamoto; Nobutoshi Matsumura; Shuji Yamaguchi; Michio Yamakido; Kiyomi Taniyama; Naomi Sasaki; Ronald J. Schlemper

doi:10.1056/nejmoa001999

Abstract

Gastric cancer develops in persons infected with H. pylori but not in uninfected persons. Those with histologic findings of severe gastric atrophy, corpus-predominant gastritis, or intestinal metaplasia are at increased risk. Persons with H. pylori infection and nonulcer dyspepsia, gastric ulcers, or gastric hyperplastic polyps are also at risk, but those with duodenal ulcers are not.

Keywords

MedicineIntestinal metaplasiaGastroenterologyInternal medicineHelicobacter pyloriCancerRapid urease testGastritisAtrophic gastritisAtrophyBiopsyStomachHyperplastic PolypSerologyColorectal cancerImmunologyColonoscopyAntibody

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Publication Info

Year: 2001
Type: article
Volume: 345
Issue: 11
Pages: 784-789
Citations: 4392
Access: Closed

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APA Style

                            
                                
                                    Naomi Uemura, 
                                
                                    Shiro Okamoto, 
                                
                                    Soichiro Yamamoto
                                
                                et al.
                            
                            (2001). 
                            <i>Helicobacter pylori</i> Infection and the Development of Gastric Cancer. 
                            New England Journal of Medicine
                            , 345
                            (11)
                            , 784-789.
                            https://doi.org/10.1056/nejmoa001999
                        

Identifiers

DOI: 10.1056/nejmoa001999