Insights From the International Registry of Acute Aortic Dissection

Abstract

Acute aortic dissection (AAD) is a life-threatening condition associated with high morbidity and mortality rates, and it remains a challenge to diagnose and treat. The International Registry of Acute Aortic Dissection was established in 1996 with the mission to raise awareness of this condition and provide insights to guide diagnosis and treatment. Since then, >7300 cases have been included from >51 sites in 12 countries. Although presenting symptoms and physical findings have not changed significantly over this period, the use of computed tomography in the diagnosis has increased, and more patients are managed with interventional procedures: surgery in type A AAD and endovascular therapy in type B AAD; with these changes in care, there has been a significant decrease in overall in-hospital mortality in type A AAD but not in type B AAD. Herein, we summarized the key lessons learned from this international registry of patients with AAD over the past 20 years.

Keywords

Affiliated Institutions

• Brigham and Women's Hospital US
• Massachusetts General Hospital US
• University of Bologna IT
• Centro de Investigación Biomédica en Red ES
• University of Leicester GB
• University of Pittsburgh US
• Gleason (United States) US
• IRCCS Policlinico San Donato IT
• University of Salerno IT
• Robert Bosch Hospital DE
• University of Michigan US
• Vall d'Hebron Hospital Universitari ES
• Hutchinson (Canada) CA
• Royal Brompton & Harefield NHS Foundation Trust GB
• University of Calgary CA
• Minneapolis Heart Institute Foundation US
• Washington University in St. Louis US
• University Hospital of North Norway
• University of Vienna AT

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