InterPro in 2011: new developments in the family and domain prediction database

Abstract

InterPro (http://www.ebi.ac.uk/interpro/) is a database that integrates diverse information about protein families, domains and functional sites, and makes it freely available to the public via Web-based interfaces and services. Central to the database are diagnostic models, known as signatures, against which protein sequences can be searched to determine their potential function. InterPro has utility in the large-scale analysis of whole genomes and meta-genomes, as well as in characterizing individual protein sequences. Herein we give an overview of new developments in the database and its associated software since 2009, including updates to database content, curation processes and Web and programmatic interfaces.

Keywords

Affiliated Institutions

• Centre National de la Recherche Scientifique FR
• European Bioinformatics Institute GB
• SIB Swiss Institute of Bioinformatics CH
• J. Craig Venter Institute US
• University Hospital Heidelberg DE
• École Normale Supérieure de Lyon FR
• Université de Lyon FR
• University College London GB
• Georgetown University US
• Wellcome Sanger Institute GB
• Environnement, ville, société FR
• University of London GB
• Heidelberg University DE
• Université Claude Bernard Lyon 1 FR
• University of Bristol GB

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