Abstract

Radiomics is a rapidly evolving field of research concerned with the extraction of quantitative metrics-the so-called radiomic features-within medical images. Radiomic features capture tissue and lesion characteristics such as heterogeneity and shape and may, alone or in combination with demographic, histologic, genomic, or proteomic data, be used for clinical problem solving. The goal of this continuing education article is to provide an introduction to the field, covering the basic radiomics workflow: feature calculation and selection, dimensionality reduction, and data processing. Potential clinical applications in nuclear medicine that include PET radiomics-based prediction of treatment response and survival will be discussed. Current limitations of radiomics, such as sensitivity to acquisition parameter variations, and common pitfalls will also be covered.

Keywords

RadiomicsWorkflowComputer scienceArtificial intelligenceField (mathematics)Dimensionality reductionFeature selectionMedical physicsMachine learningData miningMedicineMathematicsDatabase

MeSH Terms

HumansImage ProcessingComputer-AssistedNuclear Medicine

Affiliated Institutions

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Publication Info

Year
2020
Type
review
Volume
61
Issue
4
Pages
488-495
Citations
1518
Access
Closed

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1518
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26
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1345
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Cite This

Marius E. Mayerhoefer, Andrzej Materka, Georg Langs et al. (2020). Introduction to Radiomics. Journal of Nuclear Medicine , 61 (4) , 488-495. https://doi.org/10.2967/jnumed.118.222893

Identifiers

DOI
10.2967/jnumed.118.222893
PMID
32060219
PMCID
PMC9374044

Data Quality

Data completeness: 86%