Abstract

Most patients achieved a mid- to long-term disease-controlled state without additional treatment. Given the potential risk of GH deficiency from further treatment, it may be reasonable to consider patients clinically controlled as long as IGF-1 levels remain normalized, with careful long-term monitoring recommended.

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Year
2025
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Tomohisa Ishida, Tomohiro Kawaguchi, Yoshikazu Ogawa et al. (2025). Long-term clinical control in acromegaly patients with postoperative discordant nadir growth hormone during oral glucose tolerance test and insulin-like growth factor 1 levels: a retrospective observational study and literature review. Langenbeck s Archives of Surgery . https://doi.org/10.1007/s00423-025-03951-x

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DOI
10.1007/s00423-025-03951-x