Lung Volumes and Emphysema in Smokers with Interstitial Lung Abnormalities

Abstract

In smokers, interstitial lung abnormalities--which were present on about 1 of every 12 HRCT scans--were associated with reduced total lung capacity and a lesser amount of emphysema. (Funded by the National Institutes of Health and the Parker B. Francis Foundation; ClinicalTrials.gov number, NCT00608764.).

Keywords

MedicineLungCOPDInterstitial lung diseaseHounsfield scaleOdds ratioLung volumesDiffusing capacityVital capacityInternal medicineRadiologyComputed tomographyLung function

MeSH Terms

Cohort StudiesHumansLinear ModelsLogistic ModelsLungLung DiseasesInterstitialPulmonary DiseaseChronic ObstructivePulmonary EmphysemaPulmonary FibrosisSmokingSpirometryTomographyX-Ray ComputedTotal Lung Capacity

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Publication Info

Year: 2011
Type: article
Volume: 364
Issue: 10
Pages: 897-906
Citations: 588
Access: Closed

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APA Style

                            
                                
                                    George R. Washko, 
                                
                                    Gary M. Hunninghake, 
                                
                                    Isis E. Fernandez
                                
                                et al.
                            
                            (2011). 
                            Lung Volumes and Emphysema in Smokers with Interstitial Lung Abnormalities. 
                            New England Journal of Medicine
                            , 364
                            (10)
                            , 897-906.
                            https://doi.org/10.1056/nejmoa1007285
                        

Identifiers

DOI: 10.1056/nejmoa1007285
PMID: 21388308
PMCID: PMC3074462

Data Quality

Data completeness: 86%