Abstract

Thiazide-type diuretics are superior in preventing 1 or more major forms of CVD and are less expensive. They should be preferred for first-step antihypertensive therapy.

Keywords

MedicineDiureticCalcium channel blockerRandomized controlled trialAngiotensin-converting enzymeInternal medicineACE inhibitorPharmacologyCardiologyCalciumBlood pressure

Related Publications

Clinical Events in High-Risk Hypertensive Patients Randomly Assigned to Calcium Channel Blocker Versus Angiotensin-Converting Enzyme Inhibitor in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial

The Antihypertensive and Lipid-Lowering treatment to prevent Heart Attack Trial (ALLHAT) provides a unique opportunity to compare the long-term relative safety and efficacy of a...

2006 Hypertension 169 citations

Publication Info

Year
2002
Type
article
Volume
288
Issue
23
Pages
2981-2997
Citations
5638
Access
Closed

External Links

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Cite This

The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group (2002). Major Outcomes in High-Risk Hypertensive Patients Randomized to Angiotensin-Converting Enzyme Inhibitor or Calcium Channel Blocker vs Diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). JAMA , 288 (23) , 2981-2997. https://doi.org/10.1001/jama.288.23.2981

Identifiers

DOI
10.1001/jama.288.23.2981