Abstract

Abstract Metabolomics is a field of systems biology that draws on the scientific methods of other groups to qualitatively or quantitatively characterize small molecule metabolites in organisms, revealing their interconnections with the state of the organism at an overall relative macroscopic level. Diabetic kidney disease (DKD) is well known as a chronic metabolic disease, and metabolomics provides an excellent platform for its clinical study. A growing number of metabolomic analyses have revealed that individuals with DKD have metabolic disturbances of multiple substances in their bodies. With the continuous development and improvement of metabolomic analysis technology, the application of metabolomics in the clinical research of DKD is also expanding. This review discusses the recent progress of metabolomics in the early diagnosis, disease prognosis, and pathogenesis of DKD at the level of small molecule metabolites in vivo.

Keywords

MetabolomicsDiseaseKidney diseaseComputational biologyBioinformaticsBiologyMedicineInternal medicine

Affiliated Institutions

Related Publications

Publication Info

Year
2022
Type
review
Volume
53
Issue
6
Pages
545-551
Citations
953
Access
Closed

External Links

View on DOI.org

Social Impact

Altmetric
PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

953
OpenAlex

Cite This

Guoqing Huang, Mingcai Li, Yan Li et al. (2022). Metabolomics: A New Tool to Reveal the Nature of Diabetic Kidney Disease. Laboratory Medicine , 53 (6) , 545-551. https://doi.org/10.1093/labmed/lmac041

Identifiers

DOI
10.1093/labmed/lmac041