Abstract

Staphylococcus aureus , a major human pathogen, has a collection of virulence factors and the ability to acquire resistance to most antibiotics. This ability is further augmented by constant emergence of new clones, making S. aureus a “superbug.” Clinical use of methicillin has led to the appearance of methicillin-resistant S. aureus (MRSA).

Keywords

Staphylococcus aureusEpidemiologyMolecular epidemiologyMicrobiologyMethicillin-resistant Staphylococcus aureusStaphylococcal infectionsBiologyMedicineBacteriaGeneticsGenotypeGenePathology

MeSH Terms

Biological EvolutionGenomeBacterialHumansMethicillin-Resistant Staphylococcus aureusMolecular EpidemiologyMolecular TypingStaphylococcal Infections

Affiliated Institutions

Related Publications

Insights on Evolution of Virulence and Resistance from the Complete Genome Analysis of an Early Methicillin-Resistant <i>Staphylococcus aureus</i> Strain and a Biofilm-Producing Methicillin-Resistant <i>Staphylococcus epidermidis</i> Strain

ABSTRACT Staphylococcus aureus is an opportunistic pathogen and the major causative agent of numerous hospital- and community-acquired infections. Staphylococcus epidermidis has...

2005 Journal of Bacteriology 1012 citations

Publication Info

Year
2018
Type
review
Volume
31
Issue
4
Citations
1499
Access
Closed

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Cite This

Sahreena Lakhundi, Kunyan Zhang (2018). Methicillin-Resistant Staphylococcus aureus: Molecular Characterization, Evolution, and Epidemiology. Clinical Microbiology Reviews , 31 (4) . https://doi.org/10.1128/cmr.00020-18

Identifiers

DOI
10.1128/cmr.00020-18
PMID
30209034
PMCID
PMC6148192

Data Quality

Data completeness: 86%