Keywords
Affiliated Institutions
Related Publications
Free Radicals in the Physiological Control of Cell Function
At high concentrations, free radicals and radical-derived, nonradical reactive species are hazardous for living organisms and damage all major cellular constituents. At moderate...
Role of ubiquinone in the mitochondrial generation of hydrogen peroxide
Antimycin-inhibited bovine heart submitochondrial particles generate O2- and H2O2 with succinate as electron donor. H2O2 generation involves the action of the mitochondrial supe...
Oxidative stress, aging, and diseases
Reactive oxygen and nitrogen species (RONS) are produced by several endogenous and exogenous processes, and their negative effects are neutralized by antioxidant defenses. Oxida...
Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria
Submitochondrial particles from bovine heart in which NADH dehydrogenase is reduced by either addition of NADH and rotenone or by reversed electron transfer generate 0.9 +/- 0.1...
The Metabolic Fate of Mitochondrial Hydrogen Peroxide
Mitochondrial H 2 O 2 formation is not in equilibrium with defence mechanisms that counteract an accumulation of H 2 , in rat‐heart cell. A model for the accumulation kinetics i...
Publication Info
- Year
- 2000
- Type
- review
- Volume
- 29
- Issue
- 3-4
- Pages
- 222-230
- Citations
- 2922
- Access
- Closed
External Links
Social Impact
Social media, news, blog, policy document mentions
Citation Metrics
Cite This
Identifiers
- DOI
- 10.1016/s0891-5849(00)00317-8