Abstract
Recent technical progress in the identification and quantification of thiol modifications by redox proteomics means that many of the questions raised about the multiple roles of mitochondrial thiols can now be addressed.
Keywords
Affiliated Institutions
Related Publications
The Metabolic Fate of Mitochondrial Hydrogen Peroxide
Mitochondrial H 2 O 2 formation is not in equilibrium with defence mechanisms that counteract an accumulation of H 2 , in rat‐heart cell. A model for the accumulation kinetics i...
Mitochondrial Generation of Reactive Oxygen Species and its Role in Aerobic Life
Mitochondria are the major site for the generation of ATP at the expense of molecular oxygen. Significant fractions (approximately 2%) of oxygen are converted to the superoxide ...
How mitochondria produce reactive oxygen species
The production of ROS (reactive oxygen species) by mammalian mitochondria is important because it underlies oxidative damage in many pathologies and contributes to retrograde re...
Publication Info
- Year
- 2011
- Type
- review
- Volume
- 16
- Issue
- 6
- Pages
- 476-495
- Citations
- 330
- Access
- Closed
External Links
Social Impact
Social media, news, blog, policy document mentions
Citation Metrics
Cite This
Identifiers
- DOI
- 10.1089/ars.2011.4289