Abstract
The model-based approach reduces the variability of low expression estimates, and provides a natural method of calculating expression values for PM-only arrays. The standard errors attached to expression values can be used to assess the reliability of downstream analysis.
Keywords
ResamplingSensitivity (control systems)ReplicateHierarchical clusteringCluster analysisExpression (computer science)Biological systemData miningStatisticsReproducibilityRanking (information retrieval)Set (abstract data type)Computer sciencePattern recognition (psychology)MathematicsBiologyArtificial intelligence
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Publication Info
- Year
- 2001
- Type
- article
- Volume
- 2
- Issue
- 8
- Pages
- RESEARCH0032-RESEARCH0032
- Citations
- 977
- Access
- Closed
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Cite This
Cheng Li,
Wing Hung Wong
(2001).
Model-based analysis of oligonucleotide arrays: model validation, design issues and standard error application.
Genome biology
, 2
(8)
, RESEARCH0032-RESEARCH0032.
https://doi.org/10.1186/gb-2001-2-8-research0032
Identifiers
- DOI
- 10.1186/gb-2001-2-8-research0032