Multisequence MRI in clinically isolated syndromes and the early development of MS

P A Brex; J O’Riordan; K. A. Miszkiel; I. F. Moseley; Alan J. Thompson; Gordon T. Plant; David H. Miller

doi:10.1212/wnl.53.6.1184

Abstract

The combination of baseline MRI abnormalities and new lesions at follow-up, indicating dissemination in space and time, was associated with a high sensitivity and specificity for the early development of clinical MS. These data suggest a potential role for new diagnostic criteria for MS based on early MRI activity. Such criteria may be useful in selecting patients for therapeutic trials at this early clinical stage.

Keywords

MedicineSpinal cordMagnetic resonance imagingAsymptomaticMultiple sclerosisRadiologyPathology

MeSH Terms

AdolescentAdultBrainFemaleFollow-Up StudiesHumansMagnetic Resonance ImagingMaleMiddle AgedMultiple SclerosisPredictive Value of TestsPrognosisSensitivity and SpecificitySpinal CordSyndromeTime Factors

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Publication Info

Year: 1999
Type: article
Volume: 53
Issue: 6
Pages: 1184-1184
Citations: 117
Access: Closed

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APA Style

                            
                                
                                    P A Brex, 
                                
                                    J O’Riordan, 
                                
                                    K. A. Miszkiel
                                
                                et al.
                            
                            (1999). 
                            Multisequence MRI in clinically isolated syndromes and the early development of MS. 
                            Neurology
                            , 53
                            (6)
                            , 1184-1184.
                            https://doi.org/10.1212/wnl.53.6.1184
                        

Identifiers

DOI: 10.1212/wnl.53.6.1184
PMID: 10522870

Data Quality

Data completeness: 81%