Keywords
Affiliated Institutions
Related Publications
Augmented Expression of a Human Gene for 8-oxoguanine DNA Glycosylase (MutM) in B Lymphocytes of the Dark Zone in Lymph Node Germinal Centers
B cells that mediate normal, T cell–dependent, humoral immune responses must first pass through germinal centers (GCs) within the cortex of antigenically stimulated lymph nodes....
Somatic hypermutation in normal and transformed human B cells
Summary: In the human, most IgM + IgD + as well as CD5* peripheral blood B cells express unmutated V genes and thus can be assigned to a pre‐germinal centre (GC) stage of develo...
The human peripheral lymph node vascular addressin is a ligand for LECAM-1, the peripheral lymph node homing receptor.
The trafficking of lymphocytes from the blood and into lymphoid organs is controlled by tissue-selective lymphocyte interactions with specialized endothelial cells lining post c...
Disruption of the <i>Bcl6</i> Gene Results in an Impaired Germinal Center Formation
The Bcl6 gene has been identified from the chromosomal translocation breakpoint in B cell lymphomas, and its products are expressed highly in germinal center (GC) B cells. To in...
Follicular Dendritic Cells Carry MHC Class II-Expressing Microvesicles at Their Surface
Abstract Follicular dendritic cells (FDCs) present in lymphoid follicles play a critical role in germinal center reactions. They trap native Ags in the form of immune complexes ...
Publication Info
- Year
- 2000
- Type
- review
- Volume
- 355
- Issue
- 9200
- Pages
- 248-250
- Citations
- 152
- Access
- Closed
External Links
Social Impact
Social media, news, blog, policy document mentions
Citation Metrics
Cite This
Identifiers
- DOI
- 10.1016/s0140-6736(00)00019-2