Nivolumab versus Docetaxel in Advanced Squamous-Cell Non–Small-Cell Lung Cancer

2015 New England Journal of Medicine 8,355 citations

Abstract

Among patients with advanced, previously treated squamous-cell NSCLC, overall survival, response rate, and progression-free survival were significantly better with nivolumab than with docetaxel, regardless of PD-L1 expression level. (Funded by Bristol-Myers Squibb; CheckMate 017 ClinicalTrials.gov number, NCT01642004.).

Keywords

DocetaxelNivolumabMedicineHazard ratioInternal medicineLung cancerOncologyPopulationChemotherapyCancerConfidence intervalGastroenterologyImmunotherapy

Affiliated Institutions

Related Publications

Publication Info

Year
2015
Type
article
Volume
373
Issue
2
Pages
123-135
Citations
8355
Access
Closed

External Links

Social Impact

Social media, news, blog, policy document mentions

Citation Metrics

8355
OpenAlex

Cite This

Julie R. Brahmer, Karen L. Reckamp, Paul Baas et al. (2015). Nivolumab versus Docetaxel in Advanced Squamous-Cell Non–Small-Cell Lung Cancer. New England Journal of Medicine , 373 (2) , 123-135. https://doi.org/10.1056/nejmoa1504627

Identifiers

DOI
10.1056/nejmoa1504627